Professor Sima Setayeshgar is a theorist working on problems at the interface between physics and biology, ranging from molecular to macroscopic scales. These include evolution of higher order protein structure, physical principles underlying cellular regulatory networks and behavioral response, information processing by individual cells, and pattern formation in biological and chemical systems. A theme of this work is understanding how the laws of physics constrain biological strategies, from regulation of protein function to bacterial sensing and motility.
Distinguished Professor Jorge José has worked in different type of interdisciplinary problems in neuroscience and computational psychiatry. Starting at the neuronal level for animal models, to the stability or deficiencies in human cognition levels. Specifically, he has developed computational neuroscience models to describe the problem of binding of different precepts in the visual cortex V4, pointing out that it is a set interneurons synchronized when we pay attention selectively. Testing these results were done experimentally in in non-human primates. He has also studied the swimming behavior in larvae zebra fish to model how we go from neurons to macroscopic behavior. This involved specific neuronal properties measured experimentally to hydrodynamic equations. Recently, he has been involved in reading physiological motor signals in the peripheral nervous systems that has led to the unraveling of quantitative biomarkers of neurodevelopmental disorders, in particular in Autism spectrum disorders and ADHD.